منابع مشابه
Cited2 is required for fetal lung maturation.
Lung maturation at the terminal sac stage of lung development is characterized by a coordinated increase in terminal sac formation and vascular development in conjunction with the differentiation of alveolar type I and type II epithelial cells. The Cited2-Tcfap2a/c complex has been shown to activate transcription of Erbb3 and Pitx2c during mouse development. In this study, we show that E17.5 to...
متن کاملTranscriptional Programs Controlling Perinatal Lung Maturation
The timing of lung maturation is controlled precisely by complex genetic and cellular programs. Lung immaturity following preterm birth frequently results in Respiratory Distress Syndrome (RDS) and Broncho-Pulmonary Dysplasia (BPD), which are leading causes of mortality and morbidity in preterm infants. Mechanisms synchronizing gestational length and lung maturation remain to be elucidated. In ...
متن کاملPre- and Postnatal Lung Development, Maturation, and Plasticity Effects of oligohydramnios on lung growth and maturation in the fetal rat
Kitterman, Joseph A., Cheryl J. Chapin, Jeff N. Vanderbilt, Nicolas F. M. Porta, Louis M. Scavo, Leland G. Dobbs, Robert Ertsey, and Jon Goerke. Effects of oligohydramnios on lung growth and maturation in the fetal rat. Am J Physiol Lung Cell Mol Physiol 282: L431–L439, 2002. First published October 5, 2001; 10.1152/ ajplung.00161.2001.—Oligohydramnios (OH) retards fetal lung growth by producin...
متن کاملMaternal Synchronization of Gestational Length and Lung Maturation
Among all mammals, fetal growth and organ maturation must be precisely synchronized with gestational length to optimize survival at birth. Lack of pulmonary maturation is the major cause of infant mortality in preterm birth. Whether fetal or maternal genotypes influence the close relationship between the length of gestation and lung function at birth is unknown. Structural and biochemical indic...
متن کاملAntenatal infection/inflammation and postnatal lung maturation and injury
Chorioamnionitis is frequently associated with preterm deliveries before 30 weeks gestation. Chorioamnionitis correlates both with an increased risk of bronchopulmonary dysplasia and with a decreased risk of respiratory distress syndrome. Both interleukin-1alpha and endotoxin can induce inflammation in the fetal lungs and lung maturation after preterm birth when given by intra-amniotic injectio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1996
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19960046